Biotechnology/Biomanufacturing

Program Competencies for BTD

Upon graduation from this program, students shall have demonstrated the ability to:

  • Use the language of biotechnology.
  • Articulate, read and follow an SOP (standard operating procedure).
  • Conduct the mathematic and computational operations involved in biotechnology including use of applicable computer programs.
  • Understand and apply the regulatory requirements of cGMP (current Good Manufacturing Practices).
  • Understand the basic biology and chemistry behind the manufacturing processes.
  • Perform laboratory skills use in biotechnology and biomanufacturing.

Technical Standards1 for BTC and BTD

1

For general information about technical standards and accommodation, see Technical Standards.

Students entering this program must be able to demonstrate the ability to:

  • Comprehend textbook material at a college level.
  • Communicate and assimilate information either in spoken, printed, signed, or computer voice format.
  • Gather, analyze, and draw conclusions from data.
  • Stand for a minimum of two hours.
  • Walk for a minimum of six hours, not necessarily consecutively.
  • Stoop, bend, and twist for a minimum of 30 minutes at a time and be able to repeat this activity at frequent intervals.
  • Differentiate colors as assessed by standard color blindness evaluation.
  • Differentiate by touch: hotness/coldness, wetness/dryness, and hardness/softness.
  • Use the small muscle dexterity necessary to do such tasks as gloving, gowning, and operating controls on laboratory instrumentation.
  • Respond to spoken words, monitor signals, and instrument alarms.
  • Identify behaviors that would endanger a person’s life or safety and intervene quickly in a crisis situation with an appropriate solution.
  • Remain calm, rational, decisive, and in control at all times, especially during emergency situations.

Biotechnology/Biomanufacturing Certificate (BTC)

Biotechnology uses living organisms, usually microscopic, to manufacture drugs or other chemicals for the purpose of enhancing medical care or altering a process which improves living conditions for the general population. Careers in biotechnology/biomanufacturing will continue to advance. The Biotechnology/Biomanufacturing certificate curriculum will offer excellent academic and skill development for anticipated positions in the biotechnology industry. For more information, please call 978-630-9572.

Year 1
FallCredits
BTC 101Introduction To Biotechnology (With Application) 4
BTC 102Basic Laboratory Techniques 3
CHE 107General Chemistry I 4
Spring
BTC 191Quality and Compliance 3
BTC 120Biotechnology Experience: Biomanufacturing 4
BTC 185Industrial Microbiology 4
Professional Elective (see list below)  3-4
 Total Credits: 25-26

Professional Electives

Credits
BIO 109Biology I4
BIO 170Cell Biology4
BTC 110Biotechnology Experience: Concepts And Procedures4
CHE 108General Chemistry II4
CHE 180Instrumental Analysis4
CIS 127Computer Technologies3
ENG 106Technical Writing3
HUM 212Medical Ethics3
MAS 208Principles Of Pharmacology3
MAT 143Statistics (or higher)4

See the biotechnology/biomanufacturing program general information for program competencies and technical standards.

Campus/format

Click here for information on the campus/format.

Helpful hints

Biotechnology/ biomanufacturing will require a substantial background and interest in science and mathematics. Potential students should recognize the need for a strong background and may be required, through testing and an interview with the admissions office, to enroll in math and science courses as prerequisites.

Transfer options

For transfer options, please click here. It is recommended that you also consult with your academic advisor.

Special requirements

Technical standards must be met with or without accommodations. Students will need a grade of C or better in all BTC courses.

Career options

For career options, please click here.

Earning potential

$17.17 per hour.

Gainful Employment Program Disclosure Information

For gainful employment information, please click here.

Biotechnology/Biomanufacturing Degree (BTD)

Biotechnology uses living organisms, usually microscopic, to manufacture drugs or other chemicals for the purpose of enhancing medical care or altering a process which improves living conditions for the general population. Careers in biotechnology/biomanufacturing will continue to advance. The biotechnology/biomanufacturing curriculum will offer excellent academic and skill development for anticipated positions in the biotechnology industry. For more information, please call 978-630-9572.

Year 1
FallCredits
BIO 109Biology I 4
CHE 107General Chemistry I 4
ENG 101English Composition I 3
CIS 127Computer Technologies 3
Spring
BTC 101Introduction To Biotechnology (With Application) 4
BTC 102Basic Laboratory Techniques 3
CHE 108General Chemistry II 4
ENG 102English Composition II 3
MAT 162Introduction to Functions & Modeling (Formerly MAT 134) (OR HIGHER) 4
Year 2
Fall
BTC 185Industrial Microbiology 4
BTC 110Biotechnology Experience: Concepts And Procedures 4
HUM 212Medical Ethics 3
Professional Elective (see list below)  3-4
Spring
BTC 120Biotechnology Experience: Biomanufacturing 4
BTC 200Biotechnology Seminar 3
BTC 191Quality and Compliance 3
Social Science Elective 1 3
Health Elective (see list below)  2-4
 Total Credits: 61-64
1

Social Science Electives: ANT, ECO, GEO, HIS, POL, PSY, SOC, SSC

Professional Electives

Credits
BIO 110Biology II4
BIO 170Cell Biology4
BTC 170Cell Culture Techniques4
CHE 180Instrumental Analysis4
ENG 106Technical Writing3
MAS 208Principles Of Pharmacology3
MAT 163Pre-Calculus (or higher)4

Health Electives

Credits
BIO 101Introduction To Nutrition (formerly NUT101)3
BIO 103Human Health And Disease3
BIO 112Biology Of Cancer3
BIO 230Nutrition, Health, And Sustainability3
CHC 101Complementary Health Care3
CHC 108Transforming Stress3
CHC 220Mind-Body-Spirit Connection3
EXS 102Principles Of Anatomy And Kinesiology3
EXS 201Exercise Science And Nutrition4
PER 126Fitness And Wellness2
PER 127Weight Management through Walking and Resistance Training2
PER 130Health, Fitness, And Wellness3

Campus/format

Click here for information on the campus/format.

Helpful hints

Biotechnology/ biomanufacturing will require a substantial background and interest in science and mathematics. Potential students should recognize the need for a strong background and may be required, through testing and an interview with the admissions office, to enroll in math and science courses as prerequisites.

Transfer options

For transfer options, please click here. It is recommended that you also consult with your academic advisor.

Special requirements

Technical standards must be met with or without accommodations. Students will need a grade of C or better in all BTC courses.

Career options

For career options, please click here.

Earning potential

$17.17 per hour.

BTC Biotechnology/Biomanufact Courses

BTC 101. Introduction To Biotechnology (With Application). 4 Credits.

This course is designed to acquaint students with the diverse field of biotechnology. Topics will include a brief history of biotechnology, job opportunities in biotechnology, recombinant DNA and protein products, microbial biotechnology, plant biotechnology, medical biotechnology, DNA fingerprinting and forensic analysis. Current ethical issues such as stem cell research and cloning will also be discussed. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: ENG 098, FYE 101, MAT 096 or higher (or corequisite), RDG 098, or placement.

BTC 102. Basic Laboratory Techniques. 3 Credits.

Topics in this course are designed to develop fundamental skills in the set up of typical growth plates and media used in standard culturing of microorganisms or tissue culture as well as preparation of common solutions and reagents. In addition, students will develop fundamental skills in the use, maintenance, and calibration of common laboratory instruments like spectrophotometers and pH meters. Principles of laboratory safety, documentation, and the use of computers in the lab will also be covered. The practical aspect of the course involves preparation of media for numerous biology classes currently offered. Prerequisites: ENG 098, FYE 101, MAT 096 or higher (or corequisite), RDG 098, or placement.

BTC 110. Biotechnology Experience: Concepts And Procedures. 4 Credits.

The first of two experiential, cornerstone courses in biotechnology. The course begins by introducing the student to the role of the technician in biotechnology and GLP (or Good Laboratory Principles). An exploration of the principles of molecular genetics will be provided, including lecture topics in transcription, translation and protein expression in prokaryotes, and eukaryotes. Included in the course will be a hands-on exposure to biotechnology research tools and protocols used for DNA isolation, gene cloning, gene expression and regulation, gene sequencing, and mRNA isolation. Lab sessions will be hands on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: BTC 101, BTC 102 with a C or better.

BTC 120. Biotechnology Experience: Biomanufacturing. 4 Credits.

The second of two experiential courses, this course begins by introducing the student to the proteins and companies of biotechnology. In the remainder of the course students use bacteria, mammalian, and yeast cells to produce human proteins using tools and standard manufacturing operating procedures of biotechnology, including upstream and downstream processing of proteins, and quality control of protein production. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: BTC 101, BTC 102 with a C or better.

BTC 170. Cell Culture Techniques. 4 Credits.

This lecture/laboratory course will provide students with a solid understanding of basic sterile and aseptic cell culture techniques through the growth and maintenance of both normal and transformed adherent and suspension mammalian cells. Topics include sterile culture techniques, trypsinization and media supplementation, subculturing, cell counting, determining viability and growth curves, cryopreservation, and research applications using cell cultures. Prerequisite: BIO 109; BTC 101 and BTC 102 with a C or better. Spring.

BTC 185. Industrial Microbiology. 4 Credits.

This course covers the principles of various processes associated with the production and recovery of different bioproducts derived from prokaryotes and eukaryotes. Topics include the classification of microorganisms, media development, instrumentation, fermentation principles, mammalian and insect cell propagation, product recovery, protein purification, and the principles of current good manufacturing practices (cGMP). Lab sessions will be hands on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisite: BTC 101 with a C or better OR AQS 110, and BTC 102 with a C or better.

BTC 190. Principles of Protein Purification. 4 Credits.

The biopharmaceutical industry is focused on producing proteins as drugs to treat diseases. This course will investigate the relationship between protein structure and function, present basic methods of protein purification, and demonstrate how protein composition influences the method of purification. The concept of pH and buffers will be discussed in detail in relation to protein purification. Students will be exposed to these concepts in lecture, readings, and the lab. Lab sessions will be hands on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: BTC 101, BTC 102 (or co-requisite), CHE 203.

BTC 191. Quality and Compliance. 3 Credits.

Good Manufacturing Practice regulations (cGMPs) apply to pharmaceutical, biotech and medical device products regulated by FDA. This course explores the content and interpretation of the regulations, with emphasis on the necessary practices, procedures and documentation required to achieve full compliance. The course will utilize case studies to facilitate interpretation and application of regulations. All participants will gain a fundamental knowledge of the basis of cGMP regulations, and the necessity of implementing them in daily operations. Additionally, this course is intended to give participants an introduction to the cGMP regulations and their application to laboratory activities, manufacturing processes and support functions, as well as demonstrate the need for thorough and comprehensive GMP training and documentation. The course also provides participants with an understanding of common terminology and the role GMPs play in their day-to-day responsibilities. Consequences of non-compliance will be examined to underline the importance of implementing and maintaining a robust cGMP posture. Prerequisites: BTC 101 with a C or better OR AQS 110 and BTC 102 with a C or better.

BTC 200. Biotechnology Seminar. 3 Credits.

This is a capstone course taken in the last semester before graduation after all of the BTC courses have been successfully completed. This course will provide an in-depth review of the entire process of producing a biologic drug. Students will examine current research being conducted in the biotech industry and explore cGMP regulations through examination of FDA warning letters. As a capstone course, students will be expected to demonstrate mastery and integration of previous BTC major coursework. Prerequisites: BTC 101 and BTC 102 with a C or better; BTC 110, BTC 120(or co-requisite). Spring.

CHE Chemistry Courses

CHE 107. General Chemistry I. 4 Credits.

This course provides the student with an understanding of the fundamental principles of matter and energy. The course includes atomic and molecular structure, the periodic table, patterns of chemical reactivity, solution chemistry, stoichiometry, thermochemistry, and chemical bonding. A mathematical approach to chemical problems is used to develop problem solving skills as well as a conceptual understanding. Laboratory work is correlated with class discussion. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: ENG 098, FYE 101, MAT 096 or higher (or corequisite), RDG 098, or placement. Recommended: High school chemistry or other previous chemistry classes.

CHE 108. General Chemistry II. 4 Credits.

A continuation of CHE 107 General Chemistry I, this course covers such topics as intermolecular forces, behavior of gases, liquids and solutions, chemical kinetics, equilibrium, oxidation-reduction and electro-chemistry. A mathematical approach to chemical problems is used to develop problem solving skills as well as a conceptual understanding. Laboratory work is correlated with class discussion. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisite: CHE 107. Spring and summer.

CHE 120. Environmental Chemistry. 4 Credits.

This course is an introduction to the principles of chemistry with an emphasis on the environmental chemistry of air, energy, water and soil. It is recommended as a general science elective or as a foundation for continued study in the sciences, particularly natural resources. The following basic chemical topics will be introduced: matter classification, atomic structure, periodic table, chemical bonds, chemical formulas and names, spectroscopy, solutions, concentration, pH, moles and the use of energy. The course emphasizes an understanding of current environmental problems, such as air and water pollution, the ozone layer and energy issues. The relationships between science, technology and society are also discussed in the context of environmental issues. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: ENG 098, FYE 101, MAT 092, RDG 098, or placement. Offered occasionally.

CHE 180. Instrumental Analysis. 4 Credits.

This course will provide a background on the fundamentals of using instrumentation to measure chemical properties and concentration including sample preparation, calibration, and data analysis. The lab portion will provide hands-on experience with instrumentation used in a variety of different analytical instruments and will include experience with electrochemical analytical techniques, gas chromatography, advanced UV-VIS spectrophotometry, and High Performance Liquid Chromatography. Some physical testing may also be included. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisite: MAT 092 or placement; CHE 203, CHE 120 or CHE 107.

CHE 203. Introduction To Inorganic, Organic, And Biochemistry. 4 Credits.

This class is an introduction to the fundamentals of inorganic and organic chemistry as a foundation for biotechnology, health sciences or further study in the sciences. This survey course will introduce principles of measurement, classification of matter, energy, atomic structure and the periodic table, chemical bonding, chemical reactions, moles, solutions, acids and bases, basic organic chemistry, the four classes of biochemical and some metabolic pathways. Lab sessions will be hands-on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: ENG 098, FYE 101, MAT 092, RDG 098, or placement.

CHE 207. Organic Chemistry I. 4 Credits.

Organic chemistry is the study of carbon and its compounds. In the first semester, the structures and properties of the basic hydrocarbons and their simple substitution products will be studied. This will allow us to explore the following fundamental topics in organic chemistry: isomers, nomenclature, basic reaction mechanisms, spectroscopy (IR, NMR and MS). The functional groups will be introduced. Laboratory work will develop basic skills and techniques, and be correlated with class discussion. Lab sessions will be hands on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: CHE 108 with a grade of C or higher, ENG 102; MAT 126, MAT 143 or MAT 162. Fall.

CHE 208. Organic Chemistry II. 4 Credits.

Organic chemistry is the study of carbon and its compounds. In the second semester, the structures and properties of the substituted hydrocarbons (functional groups) will be studied. This will include their synthesis and their reactions. The use of spectroscopy (IR, NMR and MS) will be further developed. Multistep synthesis of complex organic compounds will be introduced. Laboratory work will develop more advanced skills and techniques, and be correlated with class discussion. Lab sessions will be hands on experiences revolving around and applying the topics listed in the lab section of the syllabus. Prerequisites: CHE 207 with a grade of C or higher. Spring.